| 1 |
TP53 |
P04637 |
P53_HUMAN |
Cellular tumor antigen p53 |
TP53?P53 |
Homo sapiens (Human) |
393 |
hsa:7157 |
9606.ENSP00000269305 |
| 2 |
MYC |
P01106 |
MYC_HUMAN |
Myc proto-oncogene protein |
MYC?BHLHE39 |
Homo sapiens (Human) |
439 |
hsa:4609 |
9606.ENSP00000479618 |
| 3 |
CCND1 |
P24385 |
CCND1_HUMAN |
G1/S-specific cyclin-D1 |
CCND1?BCL1, PRAD1 |
Homo sapiens (Human) |
295 |
hsa:595 |
9606.ENSP00000227507 |
| 4 |
PTEN |
P60484 |
PTEN_HUMAN |
Phosphatidylinositol 3,4,5-trisphos... |
PTEN?MMAC1, TEP1 |
Homo sapiens (Human) |
403 |
hsa:5728 |
9606.ENSP00000361021 |
| 5 |
ERBB2/HER2 |
P04626 |
ERBB2_HUMAN |
Receptor tyrosine-protein kinase er... |
ERBB2?HER2, MLN19, NEU, NGL |
Homo sapiens (Human) |
1,255 |
hsa:2064 |
9606.ENSP00000269571 |
| 6 |
ZNF703/FGFR1 |
Q9H7S9 |
ZN703_HUMAN |
Zinc finger protein 703 |
ZNF703?ZEPPO1, ZPO1 |
Homo sapiens (Human) |
590 |
hsa:80139 |
9606.ENSP00000332325 |
| 7 |
GATA3 |
P23771 |
GATA3_HUMAN |
Trans-acting T-cell-specific transc... |
GATA3 |
Homo sapiens (Human) |
443 |
hsa:2625 |
9606.ENSP00000368632 |
| 8 |
RB1 |
P06400 |
RB_HUMAN |
Retinoblastoma-associated protein |
RB1 |
Homo sapiens (Human) |
928 |
hsa:5925 |
9606.ENSP00000267163 |
| 9 |
MAP3K1 |
Q13233 |
M3K1_HUMAN |
Mitogen-activated protein kinase ki? |
MAP3K1?MAPKKK1, MEKK, MEKK1 |
Homo sapiens (Human) |
1,512 |
hsa:4214 |
9606.ENSP00000382423 |
| 10 |
MAP2K4 |
P45985 |
MP2K4_HUMAN |
Dual specificity mitogen-activated ... |
MAP2K4?JNKK1, MEK4, MKK4, PRKMK4, SEK1, SERK1, SKK1? |
Homo sapiens (Human) |
399 |
hsa:6416 |
9606.ENSP00000410402 |
| 11 |
ZNF217 |
O75362 |
ZN217_HUMAN |
Zinc finger protein 217 |
ZNF217?ZABC1 |
Homo sapiens (Human) |
1,048 |
hsa:7764 |
9606.ENSP00000360526 |
| 12 |
CDH1 |
P12830 |
CADH1_HUMAN |
Cadherin-1 |
CDH1?CDHE, UVO |
Homo sapiens (Human) |
882 |
hsa:999 |
9606.ENSP00000261769 |
| 13 |
MLL3/KMT2C |
Q8NEZ4 |
KMT2C_HUMAN |
Histone-lysine N-methyltransferase 2C, Lysine N-methyltransferase 2C, EC 2.1.1.354?(Homologous to ALR protein) (Myeloid/lymphoid or mixed-lineage leukemia protein 3) |
KMT2C?HALR, KIAA1506, MLL3 |
Homo sapiens (Human) |
4,911 |
hsa:58508 |
9606.ENSP00000262189 |
| 14 |
ARID1B |
Q8NFD5 |
ARI1B_HUMAN |
AT-rich interactive domain-containi... |
ARID1B?BAF250B, DAN15, KIAA1235, OSA2 |
Homo sapiens (Human) |
2,236 |
hsa:57492 |
9606.ENSP00000344546 |
| 15 |
CDKN2A |
P42771 |
CDN2A_HUMAN |
Cyclin-dependent kinase inhibitor 2... |
CDKN2A?CDKN2, MTS1 |
Homo sapiens (Human) |
156 |
hsa:1029 |
9606.ENSP00000418915 |
| 16 |
MLLT4 |
P55196 |
AFAD_HUMAN |
Afadin |
AFDN?AF6, MLLT4 |
Homo sapiens (Human) |
1,824 |
hsa:4301 |
9606.ENSP00000375960 |
| 17 |
AKT1/PKBa |
P31749 |
AKT1_HUMAN |
RAC-alpha serine/threonine-protein ... |
AKT1?PKB, RAC |
Homo sapiens (Human) |
480 |
hsa:207 |
9606.ENSP00000451828 |
| 18 |
FBXW7 |
Q969H0 |
FBXW7_HUMAN |
F-box/WD repeat-containing protein ... |
FBXW7?FBW7, FBX30, SEL10 |
Homo sapiens (Human) |
707 |
hsa:55294 |
9606.ENSP00000281708 |
| 19 |
ARID1A |
O14497 |
ARI1A_HUMAN |
AT-rich interactive domain-containing protein 1A, ARID domain-containing protein 1A?(B120) (BRG1-associated factor 250, BAF250) (BRG1-associated factor 250a, BAF250A) (Osa homolog 1, hOSA1) (SWI-like protein) (SWI/SNF complex protein p270) (SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin subfamily F member 1) (hELD) |
ARID1A?BAF250, BAF250A, C1orf4, OSA1, SMARCF1 |
Homo sapiens (Human) |
2,285 |
hsa:8289 |
9606.ENSP00000320485 |
| 20 |
CCND3 |
P30281 |
CCND3_HUMAN |
G1/S-specific cyclin-D3 |
CCND3 |
Homo sapiens (Human) |
292 |
hsa:896 |
9606.ENSP00000362082 |
| 21 |
CBFB |
Q13951 |
PEBB_HUMAN |
Core-binding factor subunit beta |
CBFB |
Homo sapiens (Human) |
182 |
hsa:865 |
9606.ENSP00000415151 |
| 22 |
MDM2 |
Q00987 |
MDM2_HUMAN |
E3 ubiquitin-protein ligase Mdm2 |
MDM2 |
Homo sapiens (Human) |
491 |
hsa:4193 |
9606.ENSP00000258149 |
| 23 |
CCNE1 |
P24864 |
CCNE1_HUMAN |
G1/S-specific cyclin-E1 |
CCNE1?CCNE |
Homo sapiens (Human) |
410 |
hsa:898 |
9606.ENSP00000262643 |
| 24 |
CDKN2B |
P42772 |
CDN2B_HUMAN |
Cyclin-dependent kinase 4 inhibitor... |
CDKN2B?MTS2 |
Homo sapiens (Human) |
138 |
hsa:1030 |
9606.ENSP00000276925 |
| 25 |
NCOR1 |
O75376 |
NCOR1_HUMAN |
Nuclear receptor corepressor 1 |
NCOR1?KIAA1047 |
Homo sapiens (Human) |
2,440 |
hsa:9611 |
9606.ENSP00000268712 |
| 26 |
SF3B1 |
O75533 |
SF3B1_HUMAN |
Splicing factor 3B subunit 1 |
SF3B1?SAP155 |
Homo sapiens (Human) |
1,304 |
hsa:23451 |
9606.ENSP00000335321 |
| 27 |
SPEN |
Q96T58 |
MINT_HUMAN |
Msx2-interacting protein |
SPEN?KIAA0929, MINT, SHARP |
Homo sapiens (Human) |
3,664 |
hsa:23013 |
9606.ENSP00000364912 |
| 28 |
TBX3 |
O15119 |
TBX3_HUMAN |
T-box transcription factor TBX3 |
TBX3 |
Homo sapiens (Human) |
743 |
hsa:6926 |
9606.ENSP00000257566 |
| 29 |
IGF1R |
P08069 |
IGF1R_HUMAN |
Insulin-like growth factor 1 recept... |
IGF1R |
Homo sapiens (Human) |
1,367 |
hsa:3480 |
9606.ENSP00000268035 |
| 30 |
BRCA2 |
P51587 |
BRCA2_HUMAN |
Breast cancer type 2 susceptibility... |
BRCA2?FACD, FANCD1 |
Homo sapiens (Human) |
3,418 |
hsa:675 |
9606.ENSP00000369497 |
| 31 |
NF1 |
P21359 |
NF1_HUMAN |
Neurofibromin |
NF1 |
Homo sapiens (Human) |
2,839 |
hsa:4763 |
9606.ENSP00000351015 |
| 32 |
PIK3R1 |
P27986 |
P85A_HUMAN |
Phosphatidylinositol 3-kinase regul... |
PIK3R1?GRB1 |
Homo sapiens (Human) |
724 |
hsa:5295 |
9606.ENSP00000428056 |
| 33 |
EGFR |
P00533 |
EGFR_HUMAN |
Epidermal growth factor receptor |
EGFR?ERBB, ERBB1, HER1 |
Homo sapiens (Human) |
1,210 |
hsa:1956 |
9606.ENSP00000275493 |
| 34 |
KRAS |
P01116 |
RASK_HUMAN |
GTPase KRas |
KRAS?KRAS2, RASK2 |
Homo sapiens (Human) |
189 |
hsa:3845 |
9606.ENSP00000256078 |
| 35 |
ESR1 |
P03372 |
ESR1_HUMAN |
Estrogen receptor |
ESR1?ESR, NR3A1 |
Homo sapiens (Human) |
595 |
hsa:2099 |
9606.ENSP00000405330 |
| 36 |
FOXA1 |
P55317 |
FOXA1_HUMAN |
Hepatocyte nuclear factor 3-alpha |
FOXA1?HNF3A, TCF3A |
Homo sapiens (Human) |
472 |
hsa:3169 |
9606.ENSP00000250448 |
| 37 |
MED23 |
Q9ULK4 |
MED23_HUMAN |
Mediator of RNA polymerase II trans... |
MED23?ARC130, CRSP3, DRIP130, KIAA1216, SUR2 |
Homo sapiens (Human) |
1,368 |
hsa:9439 |
9606.ENSP00000357047 |
| 38 |
CDK6 |
Q00534 |
CDK6_HUMAN |
Cyclin-dependent kinase 6 |
CDK6?CDKN6 |
Homo sapiens (Human) |
326 |
hsa:1021 |
9606.ENSP00000265734 |
| 39 |
NOTCH2 |
Q04721 |
NOTC2_HUMAN |
Neurogenic locus notch homolog prot... |
NOTCH2 |
Homo sapiens (Human) |
2,471 |
hsa:4853 |
9606.ENSP00000256646 |
| 40 |
AKT2/PKBb |
P31751 |
AKT2_HUMAN |
RAC-beta serine/threonine-protein k... |
AKT2 |
Homo sapiens (Human) |
481 |
hsa:208 |
9606.ENSP00000375892 |
| 41 |
BRCA1 |
P38398 |
BRCA1_HUMAN |
Breast cancer type 1 susceptibility... |
BRCA1?RNF53 |
Homo sapiens (Human) |
1,863 |
hsa:672 |
9606.ENSP00000418960 |
| 42 |
CTCF |
P49711 |
CTCF_HUMAN |
Transcriptional repressor CTCF |
CTCF |
Homo sapiens (Human) |
727 |
hsa:10664 |
9606.ENSP00000264010 |
| 43 |
KDM6A |
O15550 |
KDM6A_HUMAN |
Lysine-specific demethylase 6A |
KDM6A?UTX |
Homo sapiens (Human) |
1,401 |
hsa:7403 |
9606.ENSP00000367203 |
| 44 |
SETD2 |
Q9BYW2 |
SETD2_HUMAN |
Histone-lysine N-methyltransferase ... |
SETD2?HIF1, HYPB, KIAA1732, KMT3A, SET2? |
Homo sapiens (Human) |
2,564 |
hsa:29072 |
9606.ENSP00000386759 |
| 45 |
CREBBP |
Q92793 |
CBP_HUMAN |
CREB-binding protein |
CREBBP?CBP |
Homo sapiens (Human) |
2,442 |
hsa:1387 |
9606.ENSP00000262367 |
| 46 |
DNMT3A |
Q9Y6K1 |
DNM3A_HUMAN |
DNA (cytosine-5)-methyltransferase ... |
DNMT3A |
Homo sapiens (Human) |
912 |
hsa:1788 |
9606.ENSP00000264709 |
| 47 |
FOXP1 |
Q9H334 |
FOXP1_HUMAN |
Forkhead box protein P1 |
FOXP1?HSPC215 |
Homo sapiens (Human) |
677 |
hsa:27086 |
9606.ENSP00000484803 |
| 48 |
MLL2 |
O14686 |
KMT2D_HUMAN |
Histone-lysine N-methyltransferase ... |
KMT2D?ALR, MLL2, MLL4 |
Homo sapiens (Human) |
5,537 |
hsa:8085 |
9606.ENSP00000301067 |
| 49 |
RUNX1 |
Q01196 |
RUNX1_HUMAN |
Runt-related transcription factor 1 |
RUNX1?AML1, CBFA2 |
Homo sapiens (Human) |
453 |
hsa:861 |
9606.ENSP00000300305 |
| 50 |
USP9X |
Q93008 |
USP9X_HUMAN |
Probable ubiquitin carboxyl-termina... |
USP9X?DFFRX, FAM, USP9 |
Homo sapiens (Human) |
2,554 |
hsa:8239 |
9606.ENSP00000316357 |
| 51 |
XBP1 |
P17861 |
XBP1_HUMAN |
X-box-binding protein 1 |
XBP1?TREB5, XBP2 |
Homo sapiens (Human) |
261 |
hsa:7494 |
9606.ENSP00000216037 |
| 52 |
PDGFRA |
P16234 |
PGFRA_HUMAN |
Platelet-derived growth factor rece... |
PDGFRA?PDGFR2, RHEPDGFRA |
Homo sapiens (Human) |
1,089 |
hsa:5156 |
9606.ENSP00000257290 |
| 53 |
ATR |
Q13535 |
ATR_HUMAN |
Serine/threonine-protein kinase ATR |
ATR?FRP1 |
Homo sapiens (Human) |
2,644 |
hsa:545 |
9606.ENSP00000343741 |
| 54 |
ERBB3 |
P21860 |
ERBB3_HUMAN |
Receptor tyrosine-protein kinase er... |
ERBB3?HER3 |
Homo sapiens (Human) |
1,342 |
hsa:2065 |
9606.ENSP00000267101 |
| 55 |
FGFR2 |
P21802 |
FGFR2_HUMAN |
Fibroblast growth factor receptor 2 |
FGFR2?BEK, KGFR, KSAM |
Homo sapiens (Human) |
821 |
hsa:2263 |
9606.ENSP00000410294 |
| 56 |
PALB2 |
Q86YC2 |
PALB2_HUMAN |
Partner and localizer of BRCA2 |
PALB2?FANCN |
Homo sapiens (Human) |
1,186 |
hsa:79728 |
9606.ENSP00000261584 |
| 57 |
RHOA |
P61586 |
RHOA_HUMAN |
Transforming protein RhoA |
RHOA?ARH12, ARHA, RHO12 |
Homo sapiens (Human) |
193 |
hsa:387 |
9606.ENSP00000400175 |
| 58 |
SMAD4 |
Q13485 |
SMAD4_HUMAN |
Mothers against decapentaplegic hom... |
SMAD4?DPC4, MADH4 |
Homo sapiens (Human) |
552 |
hsa:4089 |
9606.ENSP00000341551 |
| 59 |
ATM |
Q13315 |
ATM_HUMAN |
Serine-protein kinase ATM |
ATM |
Homo sapiens (Human) |
3,056 |
hsa:472 |
9606.ENSP00000278616 |
| 60 |
ATRX |
P46100 |
ATRX_HUMAN |
Transcriptional regulator ATRX |
ATRX?RAD54L, XH2 |
Homo sapiens (Human) |
2,492 |
hsa:546 |
9606.ENSP00000362441 |
| 61 |
AXIN1 |
O15169 |
AXIN1_HUMAN |
Axin-1 |
AXIN1?AXIN |
Homo sapiens (Human) |
862 |
hsa:8312 |
9606.ENSP00000262320 |
| 62 |
BCOR |
Q6W2J9 |
BCOR_HUMAN |
BCL-6 corepressor |
BCOR?KIAA1575 |
Homo sapiens (Human) |
1,755 |
hsa:54880 |
9606.ENSP00000367705 |
| 63 |
CDKN1B |
P46527 |
CDN1B_HUMAN |
Cyclin-dependent kinase inhibitor 1... |
CDKN1B?KIP1 |
Homo sapiens (Human) |
198 |
hsa:1027 |
9606.ENSP00000228872 |
| 64 |
CUX1 |
P39880 |
CUX1_HUMAN |
Homeobox protein cut-like 1 |
CUX1?CUTL1 |
Homo sapiens (Human) |
1,505 |
|
9606.ENSP00000353401 |
| 65 |
GNAS |
Q5JWF2 |
GNAS1_HUMAN |
Guanine nucleotide-binding protein ... |
GNAS?GNAS1 |
Homo sapiens (Human) |
1,037 |
|
9606.ENSP00000360141 |
| 66 |
MLH1 |
P40692 |
MLH1_HUMAN |
DNA mismatch repair protein Mlh1 |
MLH1?COCA2 |
Homo sapiens (Human) |
756 |
hsa:4292 |
9606.ENSP00000231790 |
| 67 |
NOTCH1 |
P46531 |
NOTC1_HUMAN |
Neurogenic locus notch homolog prot... |
NOTCH1?TAN1 |
Homo sapiens (Human) |
2,555 |
hsa:4851 |
9606.ENSP00000277541 |
| 68 |
PHF6 |
Q8IWS0 |
PHF6_HUMAN |
PHD finger protein 6 |
PHF6?CENP-31, KIAA1823 |
Homo sapiens (Human) |
365 |
hsa:84295 |
9606.ENSP00000329097 |
| 69 |
SMARCA4 |
P51532 |
SMCA4_HUMAN |
Transcription activator BRG1 |
SMARCA4?BAF190A, BRG1, SNF2B, SNF2L4 |
Homo sapiens (Human) |
1,647 |
hsa:6597 |
9606.ENSP00000395654 |
| 70 |
STAG2 |
Q8N3U4 |
STAG2_HUMAN |
Cohesin subunit SA-2 |
STAG2?SA2 |
Homo sapiens (Human) |
1,231 |
hsa:10735 |
9606.ENSP00000218089 |
| 71 |
ZFP36L1 |
Q07352 |
TISB_HUMAN |
mRNA decay activator protein ZFP36L... |
ZFP36L1?BERG36, BRF1, ERF1, RNF162B, TIS11B |
Homo sapiens (Human) |
338 |
hsa:677 |
9606.ENSP00000388402 |
| 72 |
APC |
P25054 |
APC_HUMAN |
Adenomatous polyposis coli protein |
APC?DP2.5 |
Homo sapiens (Human) |
2,843 |
hsa:324 |
9606.ENSP00000257430 |
| 73 |
CASP8 |
Q14790 |
CASP8_HUMAN |
Caspase-8 |
CASP8?MCH5 |
Homo sapiens (Human) |
479 |
hsa:841 |
9606.ENSP00000351273 |
| 74 |
CBLB |
Q13191 |
CBLB_HUMAN |
E3 ubiquitin-protein ligase CBL-B |
CBLB?RNF56, Nbla00127 |
Homo sapiens (Human) |
982 |
hsa:868 |
9606.ENSP00000264122 |
| 75 |
CNOT3 |
O75175 |
CNOT3_HUMAN |
CCR4-NOT transcription complex subu... |
CNOT3?KIAA0691, LENG2, NOT3 |
Homo sapiens (Human) |
753 |
hsa:4849 |
9606.ENSP00000351159 |
| 76 |
ECT2L |
Q008S8 |
ECT2L_HUMAN |
Epithelial cell-transforming sequen... |
ECT2L?C6orf91, LFDH |
Homo sapiens (Human) |
904 |
hsa:345930 |
9606.ENSP00000442307 |
| 77 |
MEN1 |
O00255 |
MEN1_HUMAN |
Menin |
MEN1?SCG2 |
Homo sapiens (Human) |
615 |
hsa:4221 |
9606.ENSP00000337088 |
| 78 |
MSH2 |
P43246 |
MSH2_HUMAN |
DNA mismatch repair protein Msh2 |
MSH2 |
Homo sapiens (Human) |
934 |
hsa:4436 |
9606.ENSP00000233146 |
| 79 |
NRAS |
P01111 |
RASN_HUMAN |
GTPase NRas |
NRAS?HRAS1 |
Homo sapiens (Human) |
189 |
hsa:4893 |
9606.ENSP00000358548 |
| 80 |
PBRM1 |
Q86U86 |
PB1_HUMAN |
Protein polybromo-1 |
PBRM1?BAF180, PB1 |
Homo sapiens (Human) |
1,689 |
hsa:55193 |
9606.ENSP00000378307 |
| 81 |
PMS2 |
P54278 |
PMS2_HUMAN |
Mismatch repair endonuclease PMS2 |
PMS2?PMSL2 |
Homo sapiens (Human) |
862 |
hsa:5395 |
9606.ENSP00000265849 |
| 82 |
STK11 |
Q15831 |
STK11_HUMAN |
Serine/threonine-protein kinase STK... |
STK11?LKB1, PJS |
Homo sapiens (Human) |
433 |
hsa:6794 |
9606.ENSP00000324856 |
| 83 |
TET2 |
Q6N021 |
TET2_HUMAN |
Methylcytosine dioxygenase TET2 |
TET2?KIAA1546, Nbla00191 |
Homo sapiens (Human) |
2,002 |
hsa:54790 |
9606.ENSP00000442788 |
| 84 |
ASXL1 |
Q8IXJ9 |
ASXL1_HUMAN |
Polycomb group protein ASXL1 |
ASXL1?KIAA0978 |
Homo sapiens (Human) |
1,541 |
hsa:171023 |
9606.ENSP00000364839 |
| 85 |
BRAF |
P15056 |
BRAF_HUMAN |
Serine/threonine-protein kinase B-r... |
BRAF?BRAF1, RAFB1 |
Homo sapiens (Human) |
766 |
hsa:673 |
9606.ENSP00000288602 |
| 86 |
BUB1B |
O60566 |
BUB1B_HUMAN |
Mitotic checkpoint serine/threonine... |
BUB1B?BUBR1, MAD3L, SSK1 |
Homo sapiens (Human) |
1,050 |
hsa:701 |
9606.ENSP00000287598 |
| 87 |
CIC |
Q96RK0 |
CIC_HUMAN |
Protein capicua homolog |
CIC?KIAA0306 |
Homo sapiens (Human) |
1,608 |
hsa:23152 |
9606.ENSP00000458663 |
| 88 |
ERCC4 |
Q92889 |
XPF_HUMAN |
DNA repair endonuclease XPF |
ERCC4?ERCC11, XPF |
Homo sapiens (Human) |
916 |
hsa:2072 |
9606.ENSP00000310520 |
| 89 |
HRAS |
P01112 |
RASH_HUMAN |
GTPase HRas |
HRAS?HRAS1 |
Homo sapiens (Human) |
189 |
hsa:3265 |
9606.ENSP00000407586 |
| 90 |
NF2 |
P35240 |
MERL_HUMAN |
Merlin |
NF2?SCH |
Homo sapiens (Human) |
595 |
hsa:4771 |
9606.ENSP00000344666 |
| 91 |
PRDM1 |
O75626 |
PRDM1_HUMAN |
PR domain zinc finger protein 1 |
PRDM1?BLIMP1 |
Homo sapiens (Human) |
825 |
hsa:639 |
9606.ENSP00000358092 |
| 92 |
PREX2 |
Q70Z35 |
PREX2_HUMAN |
Phosphatidylinositol 3,4,5-trisphos... |
PREX2?DEPDC2 |
Homo sapiens (Human) |
1,606 |
hsa:80243 |
9606.ENSP00000288368 |
| 93 |
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